Allergy to
latex gloves:
causes and safe alternatives
A clear guide to choosing the right PPE for your operations and risks.

Key points:
- Three types of reaction: immediate allergy (type I, linked to latex proteins, which can lead to anaphylactic shock), delayed allergy (type IV, caused by additives such as vulcanisation accelerators) and irritant dermatitis (non-allergic, caused by powder or chemicals).
- Symptoms vary: itching, redness, hives, blisters, rhinitis, asthma, and even malaise or tachycardia. Spotting them early helps to limit exposure.
- Diagnosis relies on specialised tests: skin prick tests for type I and patch tests for type IV. It is still essential to consult an allergist to confirm the diagnosis and find the right solutions.
- There are reliable alternatives available: nitrile gloves (particularly those without accelerators), vinyl gloves for short-term use, or under-gloves and specialised synthetic gloves to minimise the risk of allergic reactions.
Allergies to latex gloves have become much less common since the widespread adoption of powder-free gloves and the increased use of nitrile, but they remain a reality for healthcare workers and certain other exposed workers. The allergy is primarily triggered by proteins in latex and manifests itself in various skin reactions.
With Medicom’s expertise, you’ll learn how to recognise the symptoms, get a diagnosis, prevent reactions and choose safe alternatives.
How to choose your PPE
depending on the situation?
Natural latex comes from the sap of the rubber tree: it contains proteins that can trigger allergic reactions. But be aware that not all problems associated with disposable gloves are necessarily linked to latex: some intolerances are actually caused by the chemical additives used during manufacture.
It is therefore essential to distinguish between an allergy to latex proteins and a reaction to synthetic rubber compounds. This distinction guides the diagnosis… and, above all, the choice of suitable equipment.

The 3 types of reactions
related to gloves
Not all skin reactions are the same: some are allergic, whilst others are simply irritant. Specialists distinguish between three main types:
Type I (unchanged): Allergy to latex proteins
An immediate allergic reaction occurs shortly after contact with latex proteins. It is mediated by IgE antibodies and can cause hives, itching or breathing difficulties. In some cases, the reaction can be severe, leading to anaphylactic shock, which requires urgent medical attention.
Even a mild reaction should be cause for concern: repeated exposure increases the risk of a severe reaction.
Type IV (delayed): contact allergy (additives)
Type IV allergy manifests itself between 48 and 72 hours after exposure. It is not caused by latex proteins but by vulcanisation accelerators, thiurams or certain antioxidants used in the manufacture of gloves.
Typical symptoms include redness, itching and blisters on the hands. This form is less severe than an immediate allergic reaction, but it damages the skin and increases the risk of infection. Alternatives are available, such as nitrile gloves without accelerators, which significantly reduce this risk.
Irritable dermatitis (not allergic)
Irritant dermatitis is not an allergy but a skin reaction to external factors: disinfectant chemicals, trapped sweat or even powder from gloves.
It manifests as redness, a burning sensation and dry skin. Although uncomfortable, it usually clears up once exposure ceases or when powder-free gloves and better hand hygiene are adopted.

Alternatives to latex gloves: which ones should you choose?
Nitrile (priority): including those without accelerators
Nitrile gloves are now the safest option: they provide an excellent barrier against infectious agents and chemicals, whilst being more comfortable than vinyl. Variants free from accelerators significantly reduce the risk of Type IV dermatitis, which is common with vulcanisation additives.
At Medicom, the range of accelerator-free nitrile gloves combines Class I DM-certified protection and Category III PPE with high-quality manufacturing, featuring models suited to both medical and industrial environments. This innovation is embodied in Pureflex® technology, incorporated into the Coverfeel range — a collection of Made in France nitrile gloves designed to combine protection, comfort and skin tolerance. These chlorine-free and accelerator-free gloves offer a soft, supple and non-irritating texture, ideal for prolonged wear in medical, dental or industrial environments.
Vinyl: when to use it (and its limitations)
Vinyl gloves are suitable for short-term use and low-risk environments, such as certain cleaning tasks or simple food contact. Their advantages include being latex-free and cost-effective.
However, their mechanical and chemical resistance is limited. They are therefore not a substitute for nitrile in demanding medical or industrial settings. When chosen carefully, they remain useful in specific situations.

Symptoms to look out for (skin, breathing, general)
Symptoms of a latex allergy vary depending on the individual’s sensitivity and the type of reaction. On the skin, symptoms include itching, pruritus, redness, blisters or hives. Respiratory symptoms include rhinitis, sneezing, asthma or difficulty breathing. Finally, general symptoms such as malaise, swelling or tachycardia may occur.
Spotting these signs early on helps to limit exposure and take action before the reaction gets worse.

Diagnosis: when to seek medical advice and what tests are involved
If you experience any suspicious reactions, it is essential to consult an allergist. The doctor will carry out a latex allergy skin test to confirm a Type I reaction (prick test, which provides a quick and sensitive result). For delayed-type allergies, they will opt for a patch test, which is applied to the skin for 48 hours to identify the additives responsible.
These tests, combined with a medical consultation, help to confirm the diagnosis and tailor preventive measures. Specialist care provides reassurance and guides patients towards the right options.

Discover Medicom gloves
Are you affected by latex allergies or do you want to minimise the risks in your establishment? Our Medicom experts are here to help you identify the models best suited to your needs.
Request a personalised quote or trial samples today to test our solutions. Together, let’s ensure your teams are fully protected and that you can operate with complete peace of mind.






